Founded in 1985, Intersouth Partners is one of the largest venture capital funds in North Carolina and one of the prime venture capital firms in the Southeast, having invested in several private companies. It serves various market segments, such as communication, Internet and digital media, semiconductors, software, biotechnology, pharmaceutical and many more. Some of its portfolio companies include LOC-AID, Overture Networks, Digital Optics, Neolinear, Nitronex, Semprius, Trancept Systems, Biolex Therapeutics, Paradigm Genetics, Proteon Therapeutics, etc.