Middleton High School provides a range of educational and recreational programs for students in grades 9 through 12. The school offers instruction in engineering, math, science and information technology. Middleton High School conducts several before- and after-school programs. As a magnet school, it provides various athletic opportunities, such as football, golf, soccer, swimming, tennis, wrestling and baseball. Middleton High School operates honor, interest, general and service clubs. The school additionally operates a parent-teacher-student association. Middleton High School supports extended learning, Air Force Junior Reserve Officer Training Corps and 21st Century programs. The school has a media center that maintains a collection of books. Middleton High School is governed by Hillsborough County Public Schools.