ComFrame Software Corporation was founded in Birmingham, Ala., in 1997 by Marc Guthrie and has grown its customer reach throughout the Southeast. It is a business technology company with the resources to manage a variety of projects. ComFrame Software Corporation has historically focused on project-based consulting for numerous clients, including St. Vincent s Hospital, Honda, BE & K and Vesta Insurance. ComFrame Software Corporation maintains corporate headquarters in Birmingham, Ala., and has a regional office in Nashville, Tenn.