Arno F. Spatola founded peptides International in Louisville, Kentucky in 1983. It specializes in a variety of peptides and peptide-related products and services. The company manufactures and distributes biochemical products for research institutions throughout the world. It distributes the product line from the Peptide Institute of Osaka, Japan. The Louisville laboratory specializes in solid phase resins, amino acid derivatives, peptides, metalloprotease inhibitors and custom synthesis services. Other products include peptides, enzyme inhibitors, such as leupeptin, pepstatin A, phosphoramidon, ubenimex, MMPs, TAPI and proteasome, enzyme substrates, peptide toxins and antisera, amino acids, resins, reagents for solid phase synthesis and combinatorial chemistry.