Established in 1997, San Elizario High School offers a variety of learning and extracurricular programs. It enrolls students in grades nine through 12. The school provides a range of subjects, such as reading, math, science, social studies, English, and health and physical education. It organizes several special programs that include professional development and new teacher orientation programs, workday events, and fall and spring parent conferences. The school has a guidance division that assists students in their homework. Additionally, it has a library that offers newspapers, magazines, research options and access to card catalogs. The school is located in San Elizario, Texas and is operated by the San Elizario Independent School District.